A clinical trial to compare lower(hemoglobin threshold for PRBC transfusion 7 gm/dl) vs higher hemoglobin threshold (hemoglobin threshold for PRBC transfusion 9 gm/dl) for transfusion in children with acute respiratory distress syndrome
- Conditions
- Health Condition 1: null- Pediatric Acute Respiratory Distress Syndrome(ARDS)
- Registration Number
- CTRI/2017/01/007726
- Lead Sponsor
- PGIMER CHANDIGARH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 50
Children aged 1 month- 12 years admitted to our hospital and satisfying the criteria for the diagnosis of ARDS based on the recent pediatric specific definition proposed by Pediatric Acute Lung Injury Consensus Conference Group investigators any time during the hospital stay and on invasive mechanical ventilation and having atleast one hemoglobin level less than 9 gm/dl within 1 week of diagnosis of ARDS with no exclusion criteria will be included in study. .
1 Those who deny consent to participate in the study.
2 Patients with cyanotic heart disease.
3 Patients with acute hemorrhagic shock.
4 Patients with chronic hemolytic Anemia
5 Patients who had previous adverse reaction to transfusion.
6 Patients with hematological and solid organ malignancy.
7 Patients who received transfusion within 48 hours before enrolling in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method