umber of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium YAG laser, a randomized sham-controlled trial

Phase 2

Completed

• Conditions: MenopauseVaginal atrophy; Erbium YAG laser; Vaginal lactobacilli; Randomized sham-controlled trial; Menopause; Vaginal atrophy; Vaginal pH

• Registration Number: TCTR20191030001
• Lead Sponsor: Ratchadapisek Sompot Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-30
• Study Completion: 2020-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 44

Inclusion Criteria

Postmenopausal patients with moderate to severe vaginal atrophy
Age more than 40 years old

Exclusion Criteria

Use of hormonal treatment in previous 3 months
Use of vaginal lubricants or moisturizer in previous 3 months
Use of drugs which applied vaginally in previous 3 months
Use of spermicide in previous 3 months
Previous vaginal surgery in 3 months
Previous vaginal laser treatment
History of genitourinary tract infection in previous 1 months
Abnormal vaginal bleeding
Pelvic organ prolapse POP-Q stage at least 2

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effect of erbium YAG laser on the number of vaginal lactobacilli in postmenopausal women 2 months Vaginal gram stain

Secondary Outcome Measures

Name	Time	Method
vaginal atrophy symptoms 2 months visual analog scale,vaginal pH 2 months pH indicator strips