PREDICTive value of aggressive risk factor modification on the occurrence of major cardiovascular events in patients with embolic STROKE: PREDICT-STROKE
Not Applicable
Recruiting
- Conditions
- Atrial fibrillationStrokeCardiovascular - Other cardiovascular diseasesStroke - Ischaemic
- Registration Number
- ACTRN12620000704998
- Lead Sponsor
- Centre for Heart Rhythm Disorders, University of Adelaide
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1460
Inclusion Criteria
• At least 18 years old
• Embolic Stroke or TIA
Exclusion Criteria
• Age > 85 years
•Pregnancy or planned pregnancy within the next 24 months
•Unable to undergo MRI scan
•Major Surgery <6 months
•Valvular Disease Needing Intervention
•LVEF equal to or less than 35%
•Active Malignancy
•Autoimmune or Systemic Inflammation
•Specific Stroke Mechanisms: Patent Foramen Ovale, Vessel Dissection, Subacute Bacterial Endocarditis
•Severe Renal Dysfunction (defined as dialysis, prior or planned transplant, Cr >2.26 mg/dl or > 200 µmol/L)
•Severe Liver Dysfunction (Cirrhosis or Bilirubin > 2 x Normal or AST/ALT/ALP > 3x Normal)
•Malabsorption Disorders
•Institutional Living
•Inability to Attend Appointments
•Inability to Provide Informed Consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method