Investigating pneumonia in children under 5 years of age in Indonesia

Not Applicable

• Conditions: ower respiratory tract infection among children aged under 5 years; Infections and Infestations

• Registration Number: ISRCTN79204992
• Lead Sponsor: niversitas Diponegoro [Diponegoro University]

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-12-11
• Last Update Posted: 27 April 2020
• Study Completion: 2022-10-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

1. Cough or difficulty in breathing
2. Fast breathing:
2.1. In children aged 2 to 11 months, with breathing rate =50 breaths per min
2.2. In children aged 12 to 59 months, with breathing rate =40 breaths per min
3. First symptom appearing within the last 14 days
4. Aged under 5 years

Exclusion Criteria

1. Hospitalized for more than 24 h at enrolment
2. Cancer or history of cancer
3. History of long-term (more than 2 months) exposure to steroid drugs

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Etiology (with a primary focus on bacteria and viruses) of LRTI identified using conventional (bacterial culture) and molecular methods.

Secondary Outcome Measures

Name	Time	Method
<br> 1. Risk factors assessed using parents' and guardians' responses to a questionnaire<br> 2. Antimicrobial sensitivity patterns of isolated bacterial pathogens<br> 3. Virus identification using multiplex PCR<br> 4. Pneumococcal serotypes causing pneumonia identified using multiplex PCR and the Quellung reaction<br>