Logistic Organ Dysfunction System Role in Predicting 30-day Mortality Outcome in Intensive Care Unit of dr. Cipto Mangunkusumo General Hospital Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Indonesia University
- Enrollment
- 439
- Locations
- 1
- Primary Endpoint
- Correlation between LODS score variables with patient outcome
Study Overview
Brief Summary
LODS score for deceased ICU patients within 30 days is higher than survived ICU patients
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •adult patient (age 18 years and above) admitted to ICU
Exclusion Criteria
- •patients admitted to ICU due to burn injury, coronary artery disease, post cardiac surgery
- •patients with incomplete required information for LODS score
- •patients deceased or discharged less than 24 hours of admission
Outcomes
Primary Outcomes
Correlation between LODS score variables with patient outcome
Time Frame: 30 days from admission
Correlation between patient outcomes with each LODS score variables: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
LODS score discrimination ability
Time Frame: 30 days from admission
LODS score ability to discriminate patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
LODS score calibration
Time Frame: 30 days from admission
LODS score ability to predict patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
Secondary Outcomes
- LODS neurologic variable score: Glasgow Coma Scale (GCS)(Day 1)
- LODS cardiovascular variable score: Heart rate (HR) and/or systolic blood pressure (SBP)(Day 1)
- LODS pulmonary variable score: Partial oxygen pressure (PaO2)/Fraction of inspired oxygen (FiO2) on Mechanical Ventilation (MV) or Continuous Positive Airway Pressure (CPAP)(Day 1)
- Patient outcome(30 days from admission)
- LODS hematologic variable score: white blood cell (WBC) count and/or platelet count(Day 1)
- LODS renal variable score: serum urea nitrogen (BUN) and/or creatinine and/or urine output (UO)(Day 1)
- LODS hepatic function variable score: Serum Bilirubin and/or Prothrombin time (PT)(Day 1)
Investigators
Dita Aditianingsih
MD, PhD, Anesthesiologist Consultant
Indonesia University