Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients

Not Applicable

• Conditions: Pulmonary Veno-Occlusive Disease; Hepatic Veno-Occlusive Disease; Mucositis

• Registration Number: NCT00563498
• Lead Sponsor: Hospital Authority, Hong Kong

Brief Summary

The primary purpose of this project is to investigate if addition of glutamine, an amino acid, to standard parenteral nutrition, may improve the clinical outcome of the bone marrrow transplantation reducing the occurrence of veno-occlusive disease and severity of mucositis.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-07
• Study Completion: 2006-06
• Study First Submitted: 2007-11-21
• Study First Submitted QC: 2007-11-23
• Study First Posted: 2007-11-26
• Status Verified: 2010-07
• Last Update Submitted: 2010-07-06
• Last Update Posted: 2010-07-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Allogeneic bone marrow transplant recipients using busulfan and cyclophosphamide as conditioning.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Veno-occlusive disease	1 month
Mucositis	1 month

Secondary Outcome Measures

Name	Time	Method
Hospital stay	2 months
Use of antibiotics	2 months

Trial Locations

Locations (1)

Queen Mary Hospital; 🇨🇳 Hong Kong, China