The effect of Siriraj Ayurved Harak recipe (AVS022) on platelet aggregation in Thai healthy volunteers: a randomized, placebo, controlled trial

Phase 1

Completed

• Conditions: Platelet aggregation; Thai traditional medicine; complimentary and alternative medicine; adrenaline; Siriraj Ayurved recipe (AVS022); platelet aggregation; ADP; collagen

• Registration Number: TCTR20141212003
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2010-11-09
• Study Start: 2014-12-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

Male and female age between 18 and 45 years, considered healthy based on medical history, physical examination and laboratory test (hematology, blood biochemistry, lipid profiles, urine analysis and urine pregnancy test in only female volunteers).

Exclusion Criteria

Subject who takes drugs that affect platelet function such as aspirin,clopidogrel, etc. or has a history of drug allergy especially antipyretic drug including paracetamol or Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) or participated in other research less than 1 month from the enrollment date.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Platelet aggregation before dose and at 8, 32 hours and 7-10 days after the first dose the percentage of platelet aggregation

Secondary Outcome Measures

Name	Time	Method
AVS022 safety after dosing until 7-10 days after dose rate and type of adverse events