Validation of the accuracy of a treatment prediction system for severe hyponatremia
Not Applicable
- Conditions
- HyponatremiaD007010
- Registration Number
- JPRN-jRCTs042230147
- Lead Sponsor
- Arima Hiroshi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Patients who have given written consent and are undergoing inpatient treatment for correction of hyponatremia (serum sodium concentration <130 mEq/L) at Nagoya University Hospital, its affiliated facilities, and Gifu University Hospital.
Exclusion Criteria
1. Patients with urinary sodium concentration less than 20 mEq/L on admission
2. Patients taking high-dose steroids (hydrocortisone equivalent >30 mg/day) on admission
3. Patients who have used high-dose steroids (hydrocortisone equivalent >30 mg/day) after admission
4. Patients who used desmopressin or pitresin since admission
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of measured serum sodium concentration within +/- 2 mEq/L of the predicted serum sodium concentration at 12 hours after admission
- Secondary Outcome Measures
Name Time Method 1. Percentage of measured serum sodium concentration within +/- 2 mEq/L of the predicted serum sodium concentration at 6 hours after admission<br>2. Percentage of measured serum sodium concentration within +/- 2 mEq/L of the predicted serum sodium concentration measured every 6 hours after 12 hours of admission<br>3. Accuracy of the prediction system for treatment of hyponatremia