Nutrient And Non-Nutrient Intake, Relative Biomarkers And Their Health Impact In Different Target Populations - The NUTRIPOP-BRIDGE Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Dietary intake assessment
研究概览
简要总结
This observational study aims to provide a comprehensive evaluation of dietary habits, physical activity, biomarkers involved in nutrition, metabolic and inflammatory status as well as intestinal permeability in apparently healthy volunteers aged over 18 years working or studying at the University of Milan. Furthermore, the analysis of the gut microbiota composition along with the omics approaches will be crucial for a better comprehension of the relationship between diet and health status in this population. As part of the OnFoods project (Project code PE00000003, Concession Decree No. 1550 of 11 October 2022 adopted by the Italian Ministry of University and Research, CUP D93C22000890001, Project title "ON Foods - Research and innovation network on food and nutrition Sustainability, Safety and Security - Working ON Foods"), the results will be valuable for suggesting targeted dietary and behavioral guidance in the context of public health policies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy volunteers
- •age ≥ 18 years old
排除标准
- •Pregnancy or breastfeeding
- •not willing to sign informed consent
结局指标
主要结局
Dietary intake assessment
时间窗: At baseline and in 1 month
Two repeated 24h recalls performed at least 3 weeks apart will be used to assess energy, nutrient and non-nutrient intake.
次要结局
- Anthropometry(At baseline)
- Assessment of fat free mass and fat mass(At baseline)
- Bioelectrical phase angle(At baseline)
- MediLite to assess adherence to Mediterranean Diet(At baseline)
- MEDAS to assess adherence to Mediterranean Diet(At baseline)
- Assessment of physical activity level(At baseline)
- Assessment of food consumption based on NOVA classification(At baseline)
- Markers of nutritional status(At baseline)
- Fasting glucose and lipid profile(At baseline)
- Liver function(At baseline)
- Renal function(At baseline)
- Vitamins A, E and carotenoids(At baseline)
- Vitamin D(At baseline)
- Vitamin B12 and folate(At baseline)
- C-reactive protein(At baseline)
- Markers of systemic inflammation(At baseline)
- Markers of intestinal permeability(At baseline)
- Marker of intestinal permeability(At baseline)
- Microbiota composition(At baseline)
- Proteomic analysis(At baseline)
- Metabolomic analysis(At baseline)
- Cellular DNA damage(At baseline)