Integrated axonal fiber tracking and functional MR imaging study of brain and spinal cord for neurodegenerative disorders
Not Applicable
- Conditions
- neurodegenerative disease, epilepsy, etc.
- Registration Number
- JPRN-UMIN000016878
- Lead Sponsor
- Kyoto University Graduate School of Medicine
- Brief Summary
To observe neuronal degeneration, T2star-weihted imaging, quantitative suscpetibility mapping and NODDI(neurite orientation dispersion and density index) measurements were conducted in 4 ALS patients and 4 control subjects. As a result, NODDI measurement showed decrease of neurite density in the primary motor area. However, due to changes in collaborators, this research could not be continued and quitted.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
Not provided
Exclusion Criteria
Subjects who have difficulty in acquiring MRI revealed by a MRI questionnaire
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain MR imaging, scales for the objective assessment
- Secondary Outcome Measures
Name Time Method