MedPath

IVIGSe

Phase 1
Conditions
Idiopathic painful small fiber neuropathy or sensory neuronopathy.
Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Registration Number
CTIS2022-501717-31-00
Lead Sponsor
Sorlandet Sykehus HF
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

18-65 years, Painful sensory neuropathy fulfilling diagnostic criteria for idiopathic small fiber neuropathy or idiopathic sensory neuronopathy, Pain intensity at least 5.0 on Numeric Rating Scale (NRS) lasting at least 4 weeks, Signed written informed consent

Exclusion Criteria

Change of pain medication in the 30 days prior to inclusion, Treatment with IVIG or other immunomodulatory agents the last 4 weeks, Contraindications to IVIG ie previous stroke, myocardial infarction, or other thrombotic events, hypertension (uncorrected), smoking, diabetes, prolonged immobilization, hypercoagulable state, IgA deficiency, renal failure, ongoing heart disease, hypovolemia, previous allergic reactions to IVIG, Females who are breastfeeding, pregnant, or unwilling to practice adequate contraception throughout the study

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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