Neutrophil Side Fluorescent Light (NEU-SFL) in COVID-19 Patients Hospitalized in 2021

Centre Hospitalier Universitaire de Nīmes1 site in 1 country2,233 target enrollmentJune 2, 2022

ConditionsCOVID-19

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: COVID-19
Sponsor: Centre Hospitalier Universitaire de Nīmes
Enrollment: 2233
Locations: 1
Primary Endpoint: To compare the rate of NEU-SFL in patients hospitalized at Nimes hospital for COVID-19 in 2021, according they survived or not.
Status: Completed
Last Updated: 4 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Recently, a study showed that markers of neutrophil extracellular traps formation, a mechanism corresponding to neutrophil activation, were increased in patients who died of COVID 19 compared with survivors.

The investigators propose to analyze the NEU-SFL parameter, obtained automatically on the Sysmex™ blood count machine (Sysmex Corporation, Kobe, Japan) and which is considered as a reflect of neutrophil extracellular traps formation, in these two groups of patients. The aim was to evaluate whether this parameter could be used to predict the risk of death related to COVID 19.

Registry

clinicaltrials.gov

Start Date

June 2, 2022

End Date

December 31, 2022

Last Updated

4 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire de Nīmes

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Hospitalization for COVID 19 in 2021

Exclusion Criteria

•Patients who refused the use of their data

Outcomes

Primary Outcomes

To compare the rate of NEU-SFL in patients hospitalized at Nimes hospital for COVID-19 in 2021, according they survived or not.

Time Frame: 3 months

Data collection

Secondary Outcomes

Compare the rate of NEU-SFL in patients hospitalized at Nimes hospital for COVID-19 in 2021 who survived, between entry and discharge from Nimes hospital(3 months)
Compare the rate of NEU-SFL in patients hospitalized at Nimes hospital for COVID-19 in 2021 who died, between entry and discharge from Nimes hospital(3 months)