Ultrasonographical Study of Suprarenal Gland in High Risk Neonates
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- Adrenocortical insufficiency
研究概览
简要总结
Observation study The aim is to study the suprarenal blood flow among high-risk neonates and its relation to the risk factors
详细描述
Ultrasonographical study of the suprarenal gland in high risk newborn infants Al-Zhrraa University hospital Sample size 105 Inclusion criteria: 1- High-risk newborn 2- Need NICU admission Exclusion criteria: Cases with Major congenital anomalies and NEC Primary outcome: Abnormal suprarenal blood flow Informed consent will be obtained from all parents and mothers of the newborns enrolled in the study.
All cases will be subjected to - Full history taking: (prenatal -natal - postnatal). According to the routine admission sheet of NICU of Alzahraa University Hospital, Faculty of Medicine for girls, AL-Azhar University, Cairo, Egypt.
Through clinical examination (APGAR score -estimation of gestational age using modified Ballard score "Ballard, 1991" - body weight - severity of respiratory illness using Downs score and Silverman's score).
Laboratory investigations:
- Blood gases.
- Serum electrolytes and blood glucose.
- CBC. CRP.
- Liver and kidney functions. Radiological evaluation: in the form of Abdominal and chest x-ray. Ultrasonographical studies were done for suprarenal gland blood flow. - Statistical Analysis, Data were collected, revised, coded, and entered into the statistical package for social science (SPSS)
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 10 Days(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •High risk neonates
排除标准
- •congenital anomalies
结局指标
主要结局
Adrenocortical insufficiency
时间窗: 12 months
Blood flow velocity RI ED TMAX
次要结局
未报告次要终点
研究者
safaa ELMeneza
Professor
Al-Azhar University
