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临床试验/NCT06575504
NCT06575504已完成不适用

Ultrasonographical Study of Suprarenal Gland in High Risk Neonates

Al-Azhar University1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2023年11月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
105
试验地点
1
主要终点
Adrenocortical insufficiency

研究概览

简要总结

Observation study The aim is to study the suprarenal blood flow among high-risk neonates and its relation to the risk factors

详细描述

Ultrasonographical study of the suprarenal gland in high risk newborn infants Al-Zhrraa University hospital Sample size 105 Inclusion criteria: 1- High-risk newborn 2- Need NICU admission Exclusion criteria: Cases with Major congenital anomalies and NEC Primary outcome: Abnormal suprarenal blood flow Informed consent will be obtained from all parents and mothers of the newborns enrolled in the study.

All cases will be subjected to - Full history taking: (prenatal -natal - postnatal). According to the routine admission sheet of NICU of Alzahraa University Hospital, Faculty of Medicine for girls, AL-Azhar University, Cairo, Egypt.

Through clinical examination (APGAR score -estimation of gestational age using modified Ballard score "Ballard, 1991" - body weight - severity of respiratory illness using Downs score and Silverman's score).

Laboratory investigations:

  • Blood gases.
  • Serum electrolytes and blood glucose.
  • CBC. CRP.
  • Liver and kidney functions. Radiological evaluation: in the form of Abdominal and chest x-ray. Ultrasonographical studies were done for suprarenal gland blood flow. - Statistical Analysis, Data were collected, revised, coded, and entered into the statistical package for social science (SPSS)

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
1 Day 至 10 Days(Child)
性别
All
接受健康志愿者

入选标准

  • High risk neonates

排除标准

  • congenital anomalies

结局指标

主要结局

Adrenocortical insufficiency

时间窗: 12 months

Blood flow velocity RI ED TMAX

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

safaa ELMeneza

Professor

Al-Azhar University

研究点 (1)

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