Ultrasonographical of Suprarenal Gland in High Risk Neonates

Completed

• Conditions: Insuffeciency of the Suprarenal Gland
• Interventions: Diagnostic Test: Ultrasonographical examination

• Registration Number: NCT06575504
• Lead Sponsor: Al-Azhar University

Brief Summary

Observation study The aim is to study the suprarenal blood flow among high-risk neonates and its relation to the risk factors

Detailed Description

Ultrasonographical study of the suprarenal gland in high risk newborn infants Al-Zhrraa University hospital Sample size 105 Inclusion criteria: 1- High-risk newborn 2- Need NICU admission Exclusion criteria: Cases with Major congenital anomalies and NEC Primary outcome: Abnormal suprarenal blood flow Informed consent will be obtained from all parents and mothers of the newborns enrolled in the study.

All cases will be subjected to - Full history taking: (prenatal -natal - postnatal). According to the routine admission sheet of NICU of Alzahraa University Hospital, Faculty of Medicine for girls, AL-Azhar University, Cairo, Egypt.

Through clinical examination (APGAR score -estimation of gestational age using modified Ballard score \"Ballard, 1991\" - body weight - severity of respiratory illness using Downs score and Silverman\'s score).

Laboratory investigations:

* Blood gases.

* Serum electrolytes and blood glucose.

* CBC. CRP.

* Liver and kidney functions. Radiological evaluation: in the form of Abdominal and chest x-ray. Ultrasonographical studies were done for suprarenal gland blood flow. - Statistical Analysis, Data were collected, revised, coded, and entered into the statistical package for social science (SPSS)

Study Timeline

• Study Start: 2023-11-15
• Primary Completion: 2024-07-15
• Status Verified: 2024-08
• Study Completion: 2024-08-15
• Study First Submitted: 2024-08-26
• Study First Submitted QC: 2024-08-26
• Last Update Submitted: 2024-08-26
• Study First Posted: 2024-08-28
• Last Update Posted: 2024-08-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

• High risk neonates

Exclusion Criteria

• congenital anomalies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Neonates	Ultrasonographical examination	High risk newborn infants admitted to NICU

Primary Outcome Measures

Name	Time	Method
Adrenocortical insufficiency	12 months	Blood flow velocity RI ED TMAX

Trial Locations

Locations (1)

Faculty of medicine for girls; 🇪🇬 Cairo, Pediatrics/neonatology, Egypt