COMPARISON OF FRACTIONATED DOSE WITH BOLUS DOSE OF 0.5 PERCENT HYPERBARIC BUPIVACAINE IN SPINAL ANAESTHESIA FOR PATIENTS UNDERGOING CAESAREAN SECTION
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Severity of pain assessment using VAS pain score and modified bromage scale
研究概览
简要总结
This study is a comparative randomised observational study of fractionated with bolus dose of 0.5% hyperbaric bupivacaine in spinal anaesthesia for patients undergoing caesarean section. The comparison between fractionated and bolus doses of hyperbaric bupivacaine in spinal anesthesia for cesarean section involves evaluating their effects on both maternal and fetal outcomes, as well as the quality of anesthesia, side effects, and duration of action. Total 60 patients will be randomly selected which belongs to ASA I -III. 60 patients will be divided into two groups 30 in each by using sealed envelope technique. One group will receive drug as bolus and other will receive drug as fractionated and drug will be given to pregnant females via spinal anaesthesia under all aseptic precautions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 21.00 Year(s) 至 36.00 Year(s)（—）
- 性别
- Female
入选标准
- •Physical status I-III according to American Society of Anaesthesiologist 2) Singleton live pregnancies more than 37 weeks of gestation for elective or emergency caesarean 3) Body mass index less than 30.
排除标准
- •Patients wit pre-existing diseases like cardiovascular or cerebrovascular disease or pregnancy induced hypertension 2) Severely altered mental status 3)Spinal deformities 4) History of laminectomy 5) Any contraindication to spinal anaesthesia 6) Emergency caesarean section who cannot be explained about the study due to paucity of time.
结局指标
主要结局
Severity of pain assessment using VAS pain score and modified bromage scale
时间窗: 2,4,6,8,10,15,20,30,40,50 and 60 mins
次要结局
- 1) Hemodynamic parameters variations(2) Block characteristics)