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Clinical Trials/CTRI/2024/10/075972
CTRI/2024/10/075972Not yet recruitingNot Applicable

Comparison of ultrasound guided modified thoracoabdominal block through perichondrial approach M TAPA with external oblique plane block EXOP versus M TAPA in laparoscopic cholecystectomy a prospective randomized double blinded study

AIIMS New Delhi1 site in 1 country75 target enrollmentStarted: November 11, 2024Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
75
Locations
1
Primary Endpoint
Pain assessed by NRS score at 0,1,2,4,6,12,24 hours after surgery.

Study Overview

Brief Summary

Laparoscopic Cholecystectomy has beneficial

effects such as requiring a minimal surgical incision,

shortening the hospital stay and minimising post‐operative

pain. Conventionally regional anaesthesia techniques like

OBLIQUE SUBCOASTAL TRANSVERSUS

ABDOMINIS PLANE BLOCK (OSTAP), SERRATUS

INTERCOASTAL PLANE BLOCK (SIP)is used for

supraumbilical surgeries.

Administration of a modified thoracoabdominal

nerve block through a perichondrial approach (M‐TAPA)

has recently been identified as a technique providing

effective analgesia on the anterior and lateral

thoracoabdominal wall. It has been reported that the T5‐

T12 thoracoabdominal nerves are blocked with this method

and that it can be used as a suitable block in laparoscopic

upper abdominal surgeries. In adults, however in some

studies the analgesic effect provided by M-TAPA to lateral

abdominal was less effective.

EXTERNAL OBLIQUE MUSCLE PLANE

BLOCK is a technique that is found to be effective for

lateral abdominal wall analgesia. Some studies shows that it

may be anatomically plausible for the combined use of

these blocks to anaesthetise the entire abdominal wall.

Hence, we aim to compare the post operative pain scores of

patients undergoing lap cholecystectomy who receives M-

TAPA in combination with EXTERNAL OBLIQUE

MUSCLE PLANE BLOCK v/s patients who receives only

M-TAPA with a control group.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Double

Eligibility Criteria

Ages
18.00 Year(s) to 70.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients undergoing laparoscopic cholecystectomy 2.

Exclusion Criteria

  • Refusal of consent b.
  • Contraindications of Nerve Block c.
  • Chronic opioid or analgesic use d.
  • Allergic to study medications e.
  • Bleeding disorders f.
  • Anatomical deformity g.
  • Infection at block site h.
  • History of abdominal surgery i.
  • Conversion to open surgery.

Outcomes

Primary Outcomes

Pain assessed by NRS score at 0,1,2,4,6,12,24 hours after surgery.

Time Frame: Pain assessed by NRS score at 0,1,2,4,6,12,24 hours after surgery.

Secondary Outcomes

  • 1.Time of usage of first rescue analgesia(2.Cumulative opioid requirement in both the group)

Investigators

Sponsor
AIIMS New Delhi
Sponsor Class
Research institution
Responsible Party
Principal Investigator
Principal Investigator

Bikash Ranjan Ray

AIIMS New Delhi

Study Sites (1)

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