Dihydropyrimidine dehydrogenase (DPD) deficiency and haematological abnormalities

Completed

• Conditions: Dihydropyrimidine dehydrogenase deficiency; 10047954

• Registration Number: NL-OMON44558
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- genetically and/or biochemically confirmed DPD deficiency
- written permission to participate to the study by the participant and/or the parents/caregivers in case of children or incompetent adults

Exclusion Criteria

None

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To establish whether or not DPD deficient patients suffer from an altered white<br /><br>blood cell homeostasis, in particular that of B or T lymphocytes. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To investigate the function of white blood cells from DPD deficient patients.</p><br>