Correlation between ultrasound scan findings and abnormalities of placenta in high risk pregnancy

Not yet recruiting

• Conditions: Supervision of high risk pregnancy, unspecified,

• Registration Number: CTRI/2021/05/033458
• Lead Sponsor: Kasturba Medical College

Brief Summary

Informed consent will be obtained from all the participants

The study will recruit 145 pregnant women with gestational age > 28 weeks who fit into high risk pregnancy category(as mentioned under inclusion criteria).

Demographic details of the patient like maternal age, gestational age, parity will be taken

Ultrasound with color doppler done between 28-36 weeks period of Gestation will be noted with focus on Middle Cerebral Artery and Umbilical Artery

Immediately after delivery,the placenta will be sent to the Department of Pathology for gross and histopathological examination (as per consultant’s recommendation)

Mode of delivery,Delivery outcomes and baby’s health condition will be noted.

The Ultrasound changes in placenta will be studied and correlated with the histopathological changes in placenta and the perinatal outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-14
• Last Update Posted: 2021-06-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 145

Inclusion Criteria

Women with the below mentioned criteria 1)Hypertensive disorders of pregnancy 2)chronic Hypertension 3)Gestational Diabetes Mellitus and Pre existing Diabetes Mellitus 4)Intra uterine Growth Restriction 5)Antepartum hemorrhage 6)Recurrent pregnancy loss 7)Abnormal placenta 8)Still birth 9)2nd time preterm premature rupture of membranes 10)In vitro fertilization pregnancies with complications.

Exclusion Criteria

1)Multifetal gestations 2)singleton pregnancies with no associated co morbidities 3)High risk pregnancies with gestational age <28 weeks 4)Those who refuse the placental examination.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Perinatal outcomes like type of delivery,Birth weight of baby,Still birth,Intra uterine Death,APGAR score	High risk pregnancies more than 28 weeks until postpartum

Secondary Outcome Measures

Name	Time	Method
Histopathological changes of placenta	High risk pregnancies more than 28 weeks until post partum

Trial Locations

Locations (1)

Kasturba hospital Manipal; 🇮🇳 Udupi, KARNATAKA, India

Kasturba hospital Manipal

🇮🇳Udupi, KARNATAKA, India

Dr Pranavi

Principal investigator

09491624540

pranavi.1dasari@gmail.com