Study of effects of different amounts of drug called Dexmedetomidine which helps in reducing stress response like increasing blood pressure, heart rate, coughing etc when patients get a breathing tube removed after having laparoscopic surgery to remove their gallbladder.
Phase 2
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
- Registration Number
- CTRI/2023/12/060691
- Lead Sponsor
- Dr Janvi Vikram Thakkar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA Grade I & II patients undergoing Laparoscopic Cholecystectomy
Exclusion Criteria
- Those on ß-blockers, Digoxin, Alpha 2-adrenergic agonists or psychotropic medications
- Patients with Heart Rate below 60 per min or Blood Pressure less than 100 mmHg systolic and less than 60 mmHg diastolic
- Patients with a history of allergic reactions to drug used in study.
- Patients who required postoperative mechanical ventilation
- Pregnant or nursing woman
- Morbidly obese patients
- ASA Grade III & IV patients
- Anticipated difficult intubation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Haemodynamic changes during tracheal extubation <br/ ><br>- Airway response using 5 point scale during tracheal extubationTimepoint: During extubation
- Secondary Outcome Measures
Name Time Method - Time taken for emergence & tracheal extubation <br/ ><br>- Evaluation for presence of complications such as laryngospasm, bronchospasm, delayed recovery, respiratory depression, & bradycardiaTimepoint: During extubation