Comparison of Two Ways of Administration of the Neuromuscular Blockade in Thoracic Surgical Patients
Not Applicable
- Conditions
- euromuscular blockade
- Registration Number
- DRKS00018968
- Lead Sponsor
- Klinik für Anästhesiologie, Intensivmedizin und SchmerztherapieKrankenhaus Martha-Maria Halle Dölau
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
age over 18 years
- elective thoracical surgery with resection of lung parenchyma (at least anatomical resection)
- written informed consent to participate in the study
Exclusion Criteria
- age under 18 years
- known allergy to rocuronium sugammadex
- severe kidney impairment (GFR under 30)
- significant liver disfunction
- neuromuscular disorders
- BMI above 35 kg/m2
- current use of antiepileptic agents, lithium or medication containing quinine
- refusal to participate and the absence of written informed consent
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rating of surgical conditions using a rating scale
- Secondary Outcome Measures
Name Time Method - overall dose of administrated rocuronium (mg/kg/min Operation)<br>- the need and total number of additional boli of rocuronium<br>- time elapsed between end of neuromuscular blockade and end of the operation<br>- TOF/PTC-Count at the end of the operation, need of administration of the reversing agent sugammadex, dosis of administrated sugammadex (mg/kg)<br>- the ability of the surgeon to tell to which group the operated patient belongs<br>- practicability of the continuous administration of the neuromuscular blockade