Comparison of Thoracic Paravertebral Block and Pectoral Nerve Block

Not Applicable

Completed

• Conditions: Thoracic Paravertebral Block; Video-assisted Thoracoscopic Surgery; Postoperative Analgesia
• Interventions: Procedure: paravertebral block; Procedure: pectoral block

• Registration Number: NCT04855994
• Lead Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Brief Summary

This study aims to compare the efficacy and safety of ultrasound-guidedPECS II block with TPVB for postoperative analgesia after VATS.

Detailed Description

52 patients (ASA I-III) between 18 and 65 years of age, who were to undergo VATS, were randomized and divided into two groups. (26 patients in each of the PECS and TPVB groups) Thoracic paravertebral block was administered from two consecutive levels for TPVB group and a modified pectoral nerve block was performed in the PECS group. Postoperative analgesia was provided by intravenous morphine infusion using a patient-controlled analgesia device. Postoperative 24-hour total morphine consumption and duration of analgesia were the primary outcome measure. Perioperative remifentanil use, visual analog scale values during at rest and coughing, time of the first analgesic request, and additional analgesic consumption were recorded.

Study Timeline

• Study Start: 2017-06-28
• Primary Completion: 2018-08-28
• Study Completion: 2018-08-28
• Study First Submitted: 2021-04-09
• Study First Submitted QC: 2021-04-20
• Study First Posted: 2021-04-22
• Status Verified: 2021-07
• Last Update Submitted: 2021-07-04
• Last Update Posted: 2021-07-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Ages of 18-65
• Patients who will undergo VATS
• ASA I-II-III patients

Exclusion Criteria

• Patients with ASA IV
• Clinically diagnosis of spinal or chest wall deformity or pathology
• Clinically known local anesthetic allergy
• Morbid obesity (body mass index>40 kg m2)
• Clinically diagnosis of opioid, alcohol and substance dependence
• Clinically diagnosis of psychiatric disease
• Coagulopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
paravertebral group	paravertebral block	The investigators performed Paravertebral block to that patient group for postoperative analgesia
pectoral group	pectoral block	The investigators performed pectoral block to that patient group for postoperative analgesia

Primary Outcome Measures

Name	Time	Method
Postoperative 24-hours total morphine consumption of patients	24 hours postoperatively	This will be measured only one time by pca device at the 24th hour after surgery.

Secondary Outcome Measures

Name	Time	Method
Visual Analog Scale values of patients	24 hours postoperatively	Visual Analog Scale (VAS, 0-10; 0= no pain and 10= very severe unbearable pain) at 0-1-2-4-8-12 and 24th hours

Trial Locations

Locations (1)

Bakirkoy Dr. Sadi Konuk Research and Training Hospital; 🇹🇷 Istanbul, Bakirkoy, Turkey