Cerebral Oximetry when VEntilated oR Spontaneously breathing: The COVERS trial
Not Applicable
Recruiting
- Conditions
- Shoulder pathology including but not limited to shoulder instability and rotatory cuff tearsAnaesthesiology - AnaestheticsSurgery - Other surgery
- Registration Number
- ACTRN12623000143628
- Lead Sponsor
- Counties Manukau Health Research Office
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
ASA1-2 patients aged 18-70 undergoing arthroscopic shoulder surgery in the beach chair position under general anaesthesia with interscalene blockade (either ‘single shot’ or catheter-based).
Exclusion Criteria
Known cerebrovascular or peripheral vascular disease, uncontrolled hypertension, a history of severe postoperative nausea and vomiting (which may mandate a total intravenous based anaesthetic).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean change in cerebral oximetry during the operative period. This will be calculated as the difference between baseline cerebral oximetry values and mean intraoperative values, which are defined as:<br>The area under the curve (AUC) for ‘cerebral oximetry versus time’ between anaesthesia induction and wound closure, divided by duration to produce a value (AUC/t). <br>Cerebral oximetry data is downloaded digitally at the end of the case. [Time-averaged over the course of the surgery, from the start of preoxygenation to wound closure. ]
- Secondary Outcome Measures
Name Time Method The incidence of cerebral desaturation events (defined as a fall of 20% below baseline values and/or an absolute measured cerebral oxygenation value of 55% or less in either hemisphere).<br>Cerebral oximetry data is downloaded digitally at the end of the case. [Over the duration of the surgery, from the start of pre-oxygenation to wound closure. ];Changes in cerebral oximetry by ethnicity.<br>Cerebral oximetry data is downloaded digitally at the end of the case. [Over the duration of the surgery, from the start of pre-oxygenation to wound closure. ]