Effect of methadone as pain relief in day-surgery patients undergoing a laparascopic gynaecological procedure

Phase 4

Completed

• Conditions: Pain management; Gynaecological laparoscopic surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12620001131943
• Lead Sponsor: niversity of New South Wales

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-10-30
• Study Completion: 2022-05-18
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

Adults undergoing general surgery laparoscopy as well as gynaecology laparoscopy at Albury and Wodonga Hospitals
-Planned same-day discharge
-Able to speak and read English

Exclusion Criteria

-Morbid obesity
-Obstructive sleep apnoea, treated with CPAP, or diagnosed but untreated
-Significant renal or liver dysfunction
-Pregnant or breastfeeding women
-Preoperative opioid dependence
-Known or suspected allergy to methadone
-Anaesthetist wish to avoid methadone administration for any reason
-Undergoing laparoscopic bowel resection or laparoscopic nephrectomy
-Undergoing emergency laparoscopic operations (e.g. appendicectomy, ectopic pregnancy)
-Patients with long QT syndrome, and any on whom a preop ECG reveals a long QT interval
-Anyone already on an SSRI (serotonin syndrome risk)

Study & Design

• Study Type: Interventional
• Study Design: Not specified