To compare the effects of two different groups of drugs on gastric motility
Phase 4
- Conditions
- Health Condition 1: -
- Registration Number
- CTRI/2023/11/059949
- Lead Sponsor
- Dr Deekshanth Ramakrishnan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients belonging to ASA physical status I and II
2)Age 18-60 years, belonging to either gender
3)Patients giving informed written and valid consent
4)Patients undergoing upper/lower ureteric and urethral procedures under spinal anaesthesia
Exclusion Criteria
1)Patients with diabetes mellitus, chronic renal failure
2)Pregnant females
3)Patients on any drugs causing a delay in gastric emptying like aluminum hydroxide, antacids, calcium channel blockers, diphenhydramine, L-Dopa, lithium and tricyclic antidepressants(TCAs)
•Patients on pantoprazole and metaclopramide
•Patients having hypersensitivity to any of the study drugs
•Patients with prior history of gastrointestinal disease and gastrointestinal reflux disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To detect opioid-induced delay in gastric emptying in the perioperative periodTimepoint: Gastric residual volume will be measured before induction of anaesthesia, immediately after surgery, 2 hours postoperative, 6 hours postoperative
- Secondary Outcome Measures
Name Time Method 1)To find the efficacy of gastric ultrasound as a bedside tool for assessing the quality & quantity of gastric contents in the peri-operative period. <br/ ><br>2)To assess the delay in gastric emptying produced by ketamine. <br/ ><br>3)To find out if pain produces delay in gastric emptying. <br/ ><br>Timepoint: Gastric residual volume will be measured just be induction of anaesthesia, immediately after surgery, 2hours postoperative, 6hours postoperative