Influence of intraoperative opioids on quantitative sensory testing.

Not Applicable

• Conditions: opioid induced hyperalgesia (OIH); R20.8; Other and unspecified disturbances of skin sensation

• Registration Number: DRKS00009002
• Lead Sponsor: niversitätsklinikum Schleswig-Holstein,Campus Kiel,Klinik für Anästhesiologie und Operative Intensivmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-03-31
• Study Start: 2015-08-28
• Results First Posted: 2016-08-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 23

Inclusion Criteria

Age >18 years
ASA physical status I-III
elective surgery of the female breast, including segmental resections or mastectomy with or without sentinel lymph node biopsy
written informed consent

Exclusion Criteria

allergies to remifentanil, sufentanil or paracetamol, preoperative acute or chronic pain states, preoperative intake of any analgesic drugs, history of drug or alcohol abuse, renal insufficiency (serum creatinin >1,5 mg/dl), impaired liver function (GTT >100U/l), neurologic diseases that might have an impact on QST (PNP, ED), gravidity, diabetes mellitus

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
sensory thresholds (quantitative sensory testing) 22h postoperative