Is opioid free anaesthesia better than opioid anaesthesia for post operative recovery?
Not Applicable
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitisHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/12/038697
- Lead Sponsor
- Department of Anaesthesiology and Intensive Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiologists (ASA) Physical Status Grade I-II
Exclusion Criteria
1.Patients with AV block or severe bradycardia
2.Patients having BMI >30 kg/m2
3.Patients with allergy to any of the study drugs
4.Patients with cardiac, renal, hepatic and psychiatric illness.
5.H/o chronic use of opioid analgesic/ chronic steroids/ NSAIDS/ or any chronic drug therapy
6.H/o alcohol abuse
7.Patients who are pregnant or are breastfeeding
8.Patients with decreased autonomic control- elderly, diabetic, chronic hypertension, severe cardiac disease, on drugs like beta blockers or calcium channel blockers
9.Patient refusal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in postoperative recovery using QoR-40 score 24 hours after surgery.Timepoint: 24 hours after surgery.
- Secondary Outcome Measures
Name Time Method Any intraoperative bradycardia, hypotension, tachycardia, or hypertensionTimepoint: at any point of time intraoperatively;Postoperative opioid related side effectsTimepoint: within 24 hours of postoperative period;Postoperative VAS scores <br/ ><br> <br/ ><br>Timepoint: at 15 min, 30 min, 1 hr, 2 hr, 4 hr, 8 hr, 12 hr, and 24 hr postoperatively.;Requirement of postoperative analgesics in the first 24 hours after surgeryTimepoint: over first 24 hours after surgery;Sedation score in PACUTimepoint: on arrival at Post Aanaesthesia Care Unit (PACU);Time for readiness for discharge from PACU (PADSS score)Timepoint: 0 min, 15 mins, 30 mins, 45 mins, 60 mins, 1 hour 15 mins, 1 hour 30 mins, 1 hour 45 mins, 2 hours in PAC