Impact of Time-restricted Eating on Sleep, Glucose and Insulin Sensitivity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- 24 hour Continuous Glucose Monitoring (Average glucose)
研究概览
简要总结
The purpose of this research study is to see how the timing of eating impacts participants sleep and how the body responds to sugar.
详细描述
This research study is aimed to answer how the timing of eating impacts participants sleep and how the body responds to sugar. Participants must be healthy and between the ages of 18-65 to join . This research study will take 2 weeks of outpatient monitoring, and 2 different nights staying in the Sleep and Metabolism Lab. There are some risks to participating in this study, like hunger, skin irritation, discomfort with blood draws, and uncomfortableness while being observed. The investigators hope that this research will benefit the knowledge learned about circadian rhythms and metabolic disease and how the timing of eating affects these things.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adult men and women ages 18-65
- •habitual sleep duration between 7-9.25 hours
- •lived at altitude for at least 3 months.
排除标准
- •Diagnosed acute or chronic physical or psychiatric disorders;
- •diagnosed sleep disorders;
- •not participating in another research study concurrently which could increase risks, such as those involving medication or blood sampling;
- •shiftwork in the 6 months before the study; travel more then one time zone three weeks prior to the study;
- •blood donation 30 days prior to the first study visit;
- •illicit drug use, prescribed medication use (excluding over the counter products) 30 days prior to the study visit;
- •everyday nicotine use;
- •regular consumption of over 400mg caffeine per day in the past month; and consumption of over 14 alcoholic beverages a week, or more than 4 alcoholic beverages in a single day over the past month for men and consumption of over 7 alcoholic beverages a week, or more than 3 alcoholic beverages in a single day over the past month for women.
研究组 & 干预措施
Time restricted eating
For the week between the first and second overnight stay participants will be scheduled to eat a normal food quantity, but in a shorter period of time based on timing discussed with study staff. Typically, this will mean they will stop eating sometime in the afternoon and not eat again until breakfast the following day. During this time study staff will ask participants to record your meals by taking pictures and texting them to the Lab.
干预措施: Time restricted eating (Other)
Control
For the week between equipment pickup and the first overnight stay participants will maintain normal eating habits and eat across the day based on timing discussed with study staff. During this time study staff will ask participants to record meals by taking pictures and texting them to the Lab.
干预措施: Control eating (Other)
结局指标
主要结局
24 hour Continuous Glucose Monitoring (Average glucose)
时间窗: 2 weeks
Participants will wear a continuous glucose monitor for 2 weeks. Week 1 will be compared to week 2.
Oral glucose tolerance test (2 hour glucose)
时间窗: 2 weeks
Participants will complete an oral glucose tolerance test on 2 occasions (end of week 1 and end of week 2)
次要结局
未报告次要终点