Millet Products Study - Investigation of Glycemic Index and Satiety
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Determination of glycemic index based on collection of capillary plasma glucose
研究概览
简要总结
The purpose of this study is to investigate how millet incorporation into different baked product types influences glycemic response and satiety.
详细描述
The purpose of this study is to investigate how millet incorporation into different baked product types (i.e. an extruded snack versus a biscuit) influences glycemic response and satiety.
This project will examine the effect of millet, on glycemic response and satiety. To determine the effect of product matrix and processing methods, testing will be done using an extruded snack, porridge, a couscous-like product and a biscuit.
All product servings will provide 50 g of available carbohydrate and will be consumed by participants within 10 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Men, age 19-40, non-smoking
- •Normal fasting plasma glucose (<5.6 mmol/L but not below 3.6 mmol/L)
- •Normal glucose tolerance (evaluated by a 75 g oral glucose test, i.e. <7.8 mmol/L but not below 3.6 mmol/L)
- •BMI ranging from 18.5 to 29.9 kg/m2
排除标准
- •Insulin resistance (IR) will be calculated from fasting glucose and insulin values using the Homeostasis Assessment Model 2 (HOMA2). A HOMA2-IR value of greater than 1.0 will be considered indicative of insulin resistance (Levy J.C. et al. 1998).
- •Regular consumption of millet as defined by questionnaire at screening defined as more than 1x per week
- •Smoking or use of recreational drugs
- •Heavy alcohol use (defined as typically >14 drinks per week or >4 drinks on one occasion)
- •Very low fibre consumption as assessed by 24 hour food diary and self-reported fruit/vegetable/whole grain servings.
- •Restrained eater as defined by the questionnaire at screening (Three Factor Eating Questionnaire, Stunkard et al.,1985)
- •Food neophobic defined by Food Neophobia Scale questionnaire
- •Unusual sleep patterns or irregular breakfast consumption
- •Recent (i.e. >4 kg in previous 3 months) or intended weight loss or gain
- •Food allergies or any life-threatening allergy (food or otherwise)
- •Inflammatory bowel disease or other gastrointestinal disorders
- •Use of drugs which influence carbohydrate metabolism
- •Training or elite athletes
- •Inability to adhere to Study Protocols
结局指标
主要结局
Determination of glycemic index based on collection of capillary plasma glucose
时间窗: Outcome measures will be assessed at fasting, and postprandially at 15, 30, 45, 60, 90 and 120 minutes
次要结局
- Self reported ratings of satiety(Outcome measures will be assessed at fasting, and postprandially every 30 minutes over 2 hours)
研究者
Amanda Wright, Ph.D.
Associate Professor
University of Guelph