Long Term Cognitive Impact of Pediatric Acute Renal Injury
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Florida
- Enrollment
- 73
- Locations
- 1
- Primary Endpoint
- Overall health related quality of life score (HRQOL)
Study Overview
Brief Summary
The research study will investigate the longitudinal cognitive outcomes in subjects admitted as children diagnosed with sepsis who may have had acute kidney injury. Each subject will be contacted 2-15 years after their incident admission in order to solicit responses to a functional and cognitive quality of life survey. Children admitted during the same time frame that did not have kidney injury will also be surveyed.
Detailed Description
250 subjects with a prior admission for pediatric sepsis will be contacted 2-15 years following the incident admission in order to complete a survey to assess their overall quality of life. Children will be administered the Pediatric Quality of Life (PedsQL) survey with a parental section to allow for parental response. Adult subjects will take the adult version of the PedsQL.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 2 Years to 36 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Subjects may be adults or children who were admitted to the hospital with a severe infection between January 1998 to December
- •Consent from adult or parent/guardian of child to participate in study.
- •Assent from subjects between 7 and 17 years of age.
Exclusion Criteria
- •Failure or inability to complete the survey
- •Participant is unable to understand written or spoken English
- •Subjects between 7 and 17 years of age unwilling to assent.
Outcomes
Primary Outcomes
Overall health related quality of life score (HRQOL)
Time Frame: Baseline
Scale 0-100
Secondary Outcomes
No secondary outcomes reported