DRKS00028819招募中未知
imits of cognitive compensation in autism spectrum disorder: a functionally-guided, connectivity-based rTMS study of social cognition and executive funktion
VR Klinikum Düsseldorf- Kliniken der Heinrich Heine Universität0 个研究点目标入组 104 人开始时间: 2022年6月14日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 104
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Inclusion criteria for autistic subjects:
- •- Age 18 to 65
- •- No contraindications for MRI, such as metal implants or claustrophobia
- •- Autism Quotient (AQ) > 28
- •- Intelligence Quotient (IQ) >80
- •- Beck Depression Inventory (BDI) <20
- •Inclusion criteria for healthy subjects:
- •- Age 18 to 65
- •- No contraindications for MRI, such as metal implants or claustrophobia
- •- Autism Quotient (AQ) <27
- •- Intelligence Quotient (IQ) >80
- •- Beck Depression Inventory (BDI) <20
排除标准
- •Exclusion criteria for autistic and healthy subjects:
- •- History of seizures (epilepsy).
- •- Metallic foreign bodies in the skull area and pronounced tattooing in the head area
- •- Significant brain malformations or tumors, cerebral vascular events, craniocerebral trauma, neurodegenerative diseases, brain surgery
- •- Pacemaker
- •- Serious physical illnesses
- •- Tinnitus
- •- Pregnancy
- •- Taking medications that affect the seizure threshold
- •- Claustrophobia (due to MRI imaging)
- •- Current or previous treatment with deep brain stimulation, vagus nerve stimulation, other intracranial implants
- •- Age <18 or >65
- •- BDI>20 points
- •- Heavy alcohol consumption (> 60 g alcohol per day) and illegal substance abuse
- •- Lack of knowledge of the German language (due to psychometrics)
- •- glaucoma
研究者
相似试验
已完成
不适用
Cognitive Neuroscience of Autism Spectrum DisordersAsperger's DisorderChildrenAdultAutism Spectrum DisordersMental RetardationNCT01031407National Institute of Mental Health (NIMH)678
已完成
不适用
Adaptive Cognition in AutismAutism Spectrum Disorders10012562AutismNL-OMON40204Radboud Universiteit Nijmegen120
已完成
不适用
Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum DisorderAutism Spectrum Disorder (ASDAsperger's DisorderPervasive Developmental Disorder (PDD-NOS)AutismNCT01631851Yale University9
已完成
不适用
Enhancement of Behavioral and Cognitive Outcomes in Autism Spectrum Disorder Via NeurostimulationAutism Spectrum DisorderNCT05371912Christiana Care Health Services16
已完成
4 期
Biomarker-Driven Pharmacological Treatment of Adolescents With Autism Spectrum Disorder With GabapentinAutism Spectrum DisorderNCT05063656David Cochran16