YOGA-CF (Yoga Outcomes Get Assessed in Cystic Fibrosis)
- Conditions
- Cystic Fibrosis
- Interventions
- Other: Yoga
- Registration Number
- NCT06120465
- Lead Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
- Brief Summary
The goal of this clinical trial is to investigate the effects of yoga participation for adults with cystic fibrosis.
The main question it aims to answer is: does participation in yoga affect health-related quality of life for adults with cystic fibrosis?
Researchers will compare a group completing a 12-week yoga programme alongside usual cystic fibrosis care, to a group completing usual care alone to see if the addition of yoga effects health-related quality of life.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 314
Diagnosis of CF (confirmed by standard criteria; (Farrell et al. 2017))
Sixteen years of age or over
Home internet access
Ability to complete questionnaires in English
Stable CF disease as judged by the investigator, a senior CF clinician
Inability to consent for treatment or measurement
Current participation in another interventional study
Current haemoptysis (greater than streaking in the sputum)
Known pregnancy at time of recruitment
Forced expiratory volume in 1 second (FEV1) below 30% predicted at baseline
Use of ambulatory oxygen therapy, long-term oxygen therapy (LTOT) or non-invasive ventilation
Current regular participation in yoga practice
Current neurological or musculoskeletal injury which would prevent completion of yoga
Diagnosis of osteoporosis (bone density Z score <-2.5) or history of spontaneous spinal fractures
Uncontrolled gastroesophageal reflux
Acute pulmonary exacerbation within 28 days of screening
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Yoga intervention group Yoga 12 week programme of yoga - encouraged to complete 1 live class and one pre-recorded class a week. Participants will continue with usual cystic fibrosis care.
- Primary Outcome Measures
Name Time Method Respiratory Health- related quality of life - measured by the respiratory domain of the Cystic Fibrosis Questionnaire - Revised. Baseline, 12 and 24-weeks Cystic Fibrosis Questionnaire - Revised (CFQ-R) respiratory domain.Scores range from 0 to 100, with higher scores indicating better health.
- Secondary Outcome Measures
Name Time Method Other Health-related quality of life domains - captured on the Cystic Fibrosis Questionnaire - Revised (CFQ-R) Baseline, 12 and 24-weeks Cystic Fibrosis Questionnaire - Revised (CFQ-R) other eleven domains. Scores range from 0 to 100, with higher scores indicating better health.
Forced Expiratory Volume in 1 second Baseline, 12 and 24-weeks Forced expiratory volume in 1 second (FEV1) obtained through spirometry. Measured in litres and percentage predicted (using Global Lung Index equations)
Forced vital capacity (FVC) Baseline, 12 and 24-weeks Forced vital capacity obtained through spirometry. Measured in litres and percentage predicted (using Global Lung Index equations)
One Minute Sit to Stand Test Baseline, 12 and 24-weeks Participant stands up and sits down from a chair for one minute and the number of completed sit-to-stands is recorded.
Trial Locations
- Locations (1)
The Royal Brompton Hospital
🇬🇧London, Greater London, United Kingdom