NCT01188980已完成不适用
Detectable Esophageal Early Increase in Blood Supply (EIBS) in Patients With Barrett's Esophagus
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- determine if early increase blood supply (EIBS)can predict presence of Dysplasia
研究概览
简要总结
The purpose of this study is to determine if early Barrett's specialized intestinal metaplasia can be detected by measuring early increased blood supply of the esophageal tissue, with 4 Dimensional Elastic Light-Scattering Fingerprinting, (4D-ELF) technology in real time.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 years or older,
- •informed written consent,
- •patient scheduled for previously planned upper endoscopy
排除标准
- •liver disease;
- •gastric antral vascular ectasia (GAVE);any known non-esophageal aerodigestive malignancy;
- •severe cardiopulmonary disease precluding endoscopy; presence of conditions not allowing biopsy (e.g. coagulation disorder);
- •known familial polyposis syndrome (FAP, HNPCC, Juvenile polyposis, etc.);
- •known pregnancy or sexually active females of childbearing age who are not practicing an accepted form of birth control.
结局指标
主要结局
determine if early increase blood supply (EIBS)can predict presence of Dysplasia
时间窗: 10 minutes during standard upper endoscopy
To determine if early increase blood supply (EIBS), as measured in Barrett's glandular mucosa segment, can predict the presence of Dysplasia in patients with known diagnosis of Barrett's esophagus (BE).
次要结局
- determine if EIBS can predict presence of BE in patients undergoing upper endoscopy(10 minutes)
研究者
Herbert C. Wolfsen
Professor of Medicine, Mayo College of Medicine, Director of Endoscopy, Mayo Clinic Florida
Mayo Clinic
研究点 (1)
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