Development of cellular immune response after infant pneumococcal conjugate vaccinations.
Completed
- Conditions
- To determine the development of the cellular immune response (plasma B cells and memory B-cells), immediately before and after the booster of the 3+1 Prevenar® vaccination schedule at 11 months of age and before and after the challenge vaccination at 24 months of age.
- Registration Number
- NL-OMON26266
- Lead Sponsor
- etherlands Vaccine Institute
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. The children have to be of normal health (same health criteria apply as used in well-baby clinics when a child receives a vaccination, e.g. also children with small increases in temperature or cold are seen as children with normal health)
2. They have to be willing and able to allow their child to participate in the trial according to the described procedures
Exclusion Criteria
1. Previous vaccinations with Prevenar® using a schedule that differs from the Dutch 3+1 schedule
2. Previous vaccinations with other pneumoccocal vaccines
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method