Prediction and Pathogenesis of the Immune Reconstitution Inflammatory Syndrome.
Recruiting
- Conditions
- Immune Reconstitution Inflammatory Syndrome, HIV, antiretroviral therapy (ART)
- Registration Number
- NL-OMON20147
- Lead Sponsor
- Academic Medical Center, University of Amsterdam, the Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
1. Age > 18 years;
2. Informed consent;
Exclusion Criteria
1. No informed consent;
2. History of ART;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method After finalizing this observational study a nested case-control study will be performed within this cohort, in order to:<br /><br>1. Identify predicors and early diagnostic factors for the different types of IRIS, with focus on TB IRIS, cryptococcal IRIS and CMV IRIS;<br /><br>2. Obtain more insight in the pathogenesis of the different types of IRIS.
- Secondary Outcome Measures
Name Time Method 1. Obtain insoght in the epidemiological characteristics of IRIS in Gabon;<br /><br>2. Describe HIV related ophtalmological problems in this setting.