Impact of SARS-CoV-2 (COVID-19) Infection, Treated in Ambulatory Care, on Long-term Quality of Life in a Parisian Military Population

Completed

• Conditions: SARS-CoV2 Infection; Covid19
• Interventions: Other: Questionnaires COVID+; Other: Questionnaires COVID-

• Registration Number: NCT04893070
• Lead Sponsor: Direction Centrale du Service de Santé des Armées

Brief Summary

In April 2020, a meta-analysis on the long-term sequelae of respiratory syndromes related to seasonal coronaviruses (SARS and MERS) showed a significant alteration in quality of life, with in particular a decrease in physical and emotional capacities and a deterioration of social life. An improvement of the quality of life is evidenced after 6 months but without reaching the level usually observed in healthy people. The impact of SARS-CoV-2 infection on quality of life can be explained by the persistence of pleomorphic symptoms in the medium to long term. In the military population, the majority of SARS-CoV-2 cases present minor to moderate forms of the disease. Military personnel have living conditions that differ from those of the general population, in particular because of their geographic mobility, which may be responsible for isolation from the family. This isolation can be regular (we speak of "geographical celibacy" when the soldier is posted in a geographical area far from the family unit) and/or occasional, during missions on the national territory or outside. This singularity justifies a study on the impact of SARS-CoV-2 (COVID-19) infection on the quality of life in this specific population.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-05-11
• Study First Submitted QC: 2021-05-11
• Study First Posted: 2021-05-19
• Study Start: 2021-07-15
• Primary Completion: 2022-07-04
• Study Completion: 2022-07-04
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-14
• Last Update Posted: 2022-10-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 173

Inclusion Criteria

• Military personnel
• COVID+: diagnosed with COVID-19 and managed in ambulatory care since March 14th, 2020
• COVID-: not having been infected with SARS-CoV-2

Exclusion Criteria

• Hospitalized for COVID-19
• Having received a treatment against COVID-19 (other than paracetamol)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COVID+	Questionnaires COVID+	Questionnaires on COVID-19 symptomatology and quality of life
COVID-	Questionnaires COVID-	Questionnaires on quality of life

Primary Outcome Measures

Name	Time	Method
Long-term quality of life (mental component)	18 months after COVID-19 first symptoms	Mental Component Score (MCS) of the SF-36 questionnaire. The MCS ranges from 0 (bad quality of life) to 100 (good quality of life).

Secondary Outcome Measures

Name	Time	Method
Long-term quality of life (physical component)	18 months after COVID-19 first symptoms	Physical Component Score (PCS) of the SF-36 questionnaire. The PCS ranges from 0 (bad quality of life) to 100 (good quality of life).

Trial Locations

Locations (1)

1er Centre Médical des Armées; 🇫🇷 Paris, France