Cervical spondylotic myelopathy: Application of spinal diffusion-based microstructural imaging (DMI) and phase-contrast MRI

Recruiting

• Conditions: M47.12; G99.2; Myelopathy in diseases classified elsewhere

• Registration Number: DRKS00012962
• Lead Sponsor: Klinik für Neurochirurgie, Universitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

a) Symptoms of a radiculopathy od myelopthy induced by cervical degerative disease in combination with a disk herniation or cervical stenosis with contact to the cervical myelon at the MR imaging. b) Age > 18 years c) Informed consent.

Exclusion Criteria

a) MRI exclusion criteria b) Patients with prior cervical operations c) Non-degenerative causes for the pathological changings of the cervical spine (tumor, infection/inflammation, tramatic injuries) d) severe internistic pathologies e) severe neurologic or psychiatric diseases, e.g. dementia, Parkinson's disease, Multiple sclerosis, CNS inflammation, Depression, Schizophrenia

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specifity of the MIDI concerning functional (clinical or electrophysiological) or abstinent myelopathy.

Secondary Outcome Measures

Name	Time	Method
Pathologic changings in the MIDI compared to conventional MRI diagnostics in cervical myelopathy patients. Development of clinical, electrophysiological and conventional MRI changings in initial pathological altered MIDI.