Wholebody MRI In Lung Cancer StagiNg

Not Applicable

Completed

• Conditions: Lung Cancer
• Interventions: Device: MRI; Device: PET

• Registration Number: NCT02716051
• Lead Sponsor: University Hospital, Limoges

Brief Summary

Magnetic Resonnace Imaging (MRI) and Positron Emission Tomography (PET) can be both used in detection of nodes in patients with cell lung cancer (NSCLC).

However, the cardiorespiratory synchronization in the MRI, allowing acquisition of synchronous images with breathing and heart movements should increase the sensitivity of detection of pathologic mediastinal lymph nodes.

Given its high sensitivity, whole-body MRI with diffusion could possibly be at least as informative as PET, while being less expensive, not radiant.

The purpose of this study is to evaluate the performance of whole-body MRI with diffusion with cardiorespiratory synchronization, on the detection of mediastinal nodes (which are known to be less well detected by MRI) compared to PET.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-03
• Study First Submitted: 2016-03-14
• Study First Submitted QC: 2016-03-16
• Study First Posted: 2016-03-23
• Primary Completion: 2018-12
• Study Completion: 2019-06
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-02
• Last Update Posted: 2019-07-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• At least 18 years,
• Neoplasia bronchopulmonary (SCLC and NSCLC) newly diagnosed,
• Patient potentially eligible for curative treatment, but no no treatment started,
• Patients for whom a PET scan and MRI are planned

Non Inclusion Criteria:

• claustrophobia,
• Implantable Medical Device
• not compatible pacemaker type or heart valve, metal splinters eye)
• Pregnant or lactating women,

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
MRI	MRI	Wholebody MRI with cardio-pulmonary synchronization At day 1 , at the afternoon, patient will undergo an MRI analysis.
PET	PET	At day 1 , in the morning, patient will undergo an PET analysis

Primary Outcome Measures

Name	Time	Method
Th consistency of the locations of mediastinal lesions	Day 1	Node localization according to MRI and PET scan measurements on the same day

Trial Locations

Locations (1)

CHU Limoges; 🇫🇷 Limoges, France