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Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

Phase 1
Conditions
Root Canal Infection
Interventions
Registration Number
NCT04250519
Lead Sponsor
Tamil Nadu Dr.M.G.R.Medical University
Brief Summary

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

Detailed Description

Main objective of root canal retreatment is to alleviate pain and disinfect the rootcanal .However some patients may experience mild to severe pain following treatment , which leads to intake of painkillers orally for post operative pain management.

So , this study evaluates the efficiency of dexamethasone used as intracanal irrigant in post treatment pain for molar root canal retreatment sodium hypochlorite (1% \&5.25%) is used for disinfecting the canals patients will be grouped into Symptomatic and Asymptomatic patients requiring root canal retreatment and irrigants will be used in various combinations as mentioned below

1. 1% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation

2. 1% sodium hypochlorite and dexamethasone 4mg,2.5ml in each canal along with ultrasonic activation

3. 5.25% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation

4. 5.25% sodium hypochlorite and dexamethasone 4mg, 2.5ml in each canal along with ultrasonic activation calcium hydroxide is commonly used as intracanal medicament in all the patients post operative symptoms is evaluated at 12 hrs , 24 hrs,48 hrs, 72 hrs and 1 week followed by obturation is completed

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
150
Inclusion Criteria
  • teeth previously treated or attempted root canal treatment,
  • teeth with or without symptoms,
  • periapical radiograph showing evidence of inadequate previous root canal treatment or periapical changes,
  • only teeth or at least one canal where complete removal of root canal filling material was possible and reach the working length in first appointment.
Exclusion Criteria
  • patient not willing for follow up,
  • teeth with extensive cervical or apical resorption that restricted the use of sodium hypochlorite irrigation,
  • teeth with poor periodontal status, teeth not suitable for post endodontic restoration,
  • patients with acute periapical abscess,
  • patients with systemic conditions preventing radiograph exposure or multi visit treatment,
  • pregnant patients,
  • patients with allergy to any known dental materials.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
5.25% sodium hypochlorite &normal saline as placeboSodium Hypochloritesodium hypochlorite is effective in any concentration as irrigant
1% sodium hypochlorite & dexamethasone 4mg as irrigantsSodium Hypochloritesodium hypochlorite is effective in any concentration as antimicrobial irrigant and dexamethasone is anti inflammatory drug
5.25% sodium hypochlorite and dexamethasone 4mg as irrigantsSodium Hypochloritesodium hypochlorite is effective in any concentration as antimicrobial irrigant and dexamethasone is anti inflammatory drug
1% sodium hypochlorite as irrigant &normal saline as placeboSodium Hypochloritesodium hypochlorite is effective in any concentration as irrigant
Primary Outcome Measures
NameTimeMethod
post operative pain evaluation using various combination of irrigants: VAS scoreAfter 7 days

pain scale is evaluated using VISUAL ANALOG SCALE (VAS) score (1-10) 1 is minimum amount of pain experienced and 10 is maximum amount of pain experienced \[1-3\] mild pain , \[4-7\] moderate pain , \[8-10\] severe pain .

Secondary Outcome Measures
NameTimeMethod
assessment of other variables in pain scalethrough study completion, an average of 1 week

comparing the pain scale based on patients pre operative symptom ex; patient is symptomatic or Asymptomatic before treatment procedure

Trial Locations

Locations (1)

CSI college of dental sciences and research

🇮🇳

Madurai, Tamil Nadu, India

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