Assessment of Post Operative Pain Following Root Canal Retreatment in Molars Using Four Different Combination of Irrigants : A Prospective Clinical Study
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- post operative pain evaluation using various combination of irrigants: VAS score
研究概览
简要总结
This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.
详细描述
Main objective of root canal retreatment is to alleviate pain and disinfect the rootcanal .However some patients may experience mild to severe pain following treatment , which leads to intake of painkillers orally for post operative pain management.
So , this study evaluates the efficiency of dexamethasone used as intracanal irrigant in post treatment pain for molar root canal retreatment sodium hypochlorite (1% &5.25%) is used for disinfecting the canals patients will be grouped into Symptomatic and Asymptomatic patients requiring root canal retreatment and irrigants will be used in various combinations as mentioned below
- 1% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation
- 1% sodium hypochlorite and dexamethasone 4mg,2.5ml in each canal along with ultrasonic activation
- 5.25% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation
- 5.25% sodium hypochlorite and dexamethasone 4mg, 2.5ml in each canal along with ultrasonic activation calcium hydroxide is commonly used as intracanal medicament in all the patients post operative symptoms is evaluated at 12 hrs , 24 hrs,48 hrs, 72 hrs and 1 week followed by obturation is completed
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 15 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •teeth previously treated or attempted root canal treatment,
- •teeth with or without symptoms,
- •periapical radiograph showing evidence of inadequate previous root canal treatment or periapical changes,
- •only teeth or at least one canal where complete removal of root canal filling material was possible and reach the working length in first appointment.
排除标准
- •patient not willing for follow up,
- •teeth with extensive cervical or apical resorption that restricted the use of sodium hypochlorite irrigation,
- •teeth with poor periodontal status, teeth not suitable for post endodontic restoration,
- •patients with acute periapical abscess,
- •patients with systemic conditions preventing radiograph exposure or multi visit treatment,
- •pregnant patients,
- •patients with allergy to any known dental materials.
研究组 & 干预措施
1% sodium hypochlorite & dexamethasone 4mg as irrigants
sodium hypochlorite is effective in any concentration as antimicrobial irrigant and dexamethasone is anti inflammatory drug
干预措施: Sodium Hypochlorite (Drug)
1% sodium hypochlorite as irrigant &normal saline as placebo
sodium hypochlorite is effective in any concentration as irrigant
干预措施: Sodium Hypochlorite (Drug)
5.25% sodium hypochlorite and dexamethasone 4mg as irrigants
sodium hypochlorite is effective in any concentration as antimicrobial irrigant and dexamethasone is anti inflammatory drug
干预措施: Sodium Hypochlorite (Drug)
5.25% sodium hypochlorite &normal saline as placebo
sodium hypochlorite is effective in any concentration as irrigant
干预措施: Sodium Hypochlorite (Drug)
结局指标
主要结局
post operative pain evaluation using various combination of irrigants: VAS score
时间窗: After 7 days
pain scale is evaluated using VISUAL ANALOG SCALE (VAS) score (1-10) 1 is minimum amount of pain experienced and 10 is maximum amount of pain experienced \[1-3\] mild pain , \[4-7\] moderate pain , \[8-10\] severe pain .
次要结局
- assessment of other variables in pain scale(through study completion, an average of 1 week)
研究者
Dr. CT. VALLIAPPAN
Principal Investigator
Tamil Nadu Dr.M.G.R.Medical University