Does have autologous bloodwithdrawal with or without sequestration effect on the usage of allogeneic bloodproducts during heartsurgery?

• Conditions: heartsurgeryCPBautologous bloodwithdrawalsequestrationallogeneic bloodproducts

• Registration Number: NL-OMON26094
• Lead Sponsor: /A

Brief Summary

REFERENCES: <br> 1. Okamura T. Koh.E.Yokoyama S. Effect of autologous plate-rich plasma (PRP) in cardiac surgery. Kyobu Geka. 2001 May: 54 (5): 397-400 <br> 2. Stover E.P. Siegel LC, Hood PA, O¡¦Riordan GE. McKenna TR. Platelet-riche plasma sequestration, with therapeutic platelet yields, reduces allogenic in complex cardiac surgery. Anesth Analg. 2000 Mar; 90(3):509-16.<br> 3. Safwat AM, Bush R, Prevec W.Reitan JA. Intraoperative use of platelet-plasmapheresis in vascular surgery. J.Clin Anest.2002 Feb; 14(1):10-4.<br> 4. Koster A. Sanger S.KnörigFJ Kuppe H.Hetzer R Loebe. Autologous plasma and platelet sequestration at the beginning of cardiopulmonary bypass: a pilot investigation in five patients undergoing extended vascular surgery in deep hypothermia. ASAIO Journal Jan/Feb 2002.48(1): 106-109.<br> 5. Hiramatsu T.Okamura T.Imai Y.KurosawaH Aoki M.Shinóka T.Takanashi Y.Effects of autologous platelet concentrate reinfusion after open heart surgery in patient with congenital heart disease. Ann Thorac Surg. Apr. 2002; 73(4): 1282-5.<br> 6. Alfred H.Stammers,BS,CCP, John Kratz,MD, Timothy Johnson BS, Jack Crumbley, MD, and Jon Merril, BS, CCP. Journal of Extra-Corporeal Technology; 1993, 25(1)6-13.<br> 7. Crowter M, Ford I, Jeffrey RR, Urbaniak SJ, Greaves. Quality of harvested autologous platelets compared with stored donor platelets for use after cardiopulmonary bypass procedures.Br.J.Haematol. 2000 Oct; 111(1): 175-91<br> 8.R.Daane Toepasbaarheid van de plasma sequestratie techniek binnen de cardiochirurgie in het Amphia ziekenhuis Breda. NeSecc Journaal editie 2007(2) p26.<br> 9. T.Menges, I.Welters,R.M Wagner,J.Bolt, F.Dapper,G.Hempelmann. The influence of acute preoperative plasmapheresis on coagulation test, fibrinolysis, bloodloss and transfusion requirements in cardiac surgery. European J. of Cardio-Thoracic Surg. 11 (1997) 557-563.<br> 10.J.W.H. van Hees. Het effect van peri-operatieve plasmaferese bij langdurige cardiochirurgische ingrepen.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 102

Inclusion Criteria

1. Patients with a BSA > 170 dm2;

2. Patients who need to undergo CABG and or Valve surgery;

Exclusion Criteria

1. Patients with a Hemoglobin/Hematocrit ratio < 0.20 l/l after calculation with the formula for bloodwithdrawal;

2. Patients with a preoperative Trombocyt count of < 120 (x109/L);

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Will the usage of allogeneic bloodproducts be deminished after sequestration?

Secondary Outcome Measures

Name	Time	Method
Is the total amount of bloodloss in the sequestration group less compared to the total amount of bloodloss in the other groups?<br><br>