Clinical and radiographic comparison of extraction socket healing of mandibular third molars following the use of autologous platelet-rich plasma and fibrin :randomized controlled trial.
- Conditions
- bony defectOral and Gastrointestinal - Normal oral and gastrointestinal development and function
- Registration Number
- ACTRN12624001146583
- Lead Sponsor
- Ufaq rao ,shifa dental hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 12
1 Healthy males and females of age range between 18 to 45 years. 2. Patients with a demonstrable need of removal of mandibular third molar under local anaesthesia.3.Patients who are well oriented and capable and will be willing to cooperate with the requirements of the study protocol, and to provide an appropriate written informed consent.4.Mesioangular and pell and greogery class II/ class B lower third molar impactions.( will be diagnosed on periapical radiographs and OPG)5.Surgery duration less than 90 mins.
1.Pregnancy, being a nursing mother or having childbearing potential 2.Platelet dysfunction syndrome or critical thrombocytopenia.3.Under treatment with NSAIDs including aspirin, antibiotics, systematic corticosteroids, anticoagulants , immunosuppressive drugs and NOACs.4.Surgery exceeding 90 mins.5.Un cooperative patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method hard tissue bone formation after 3 months[bone density assessment tools image j histogram and adobe photoshop 3 months post extraction of mandibular third molar];clinical healing index of Landry et al will be used to evaluate the extent of soft tissue healing after third mandibular molar removal[clinical healing index of Landry et al will be used to evaluate the extent of soft tissue healing after third mandibular molar removal 7 days post extraction of mandibular third molar]
- Secondary Outcome Measures
Name Time Method