Intrauterine Instillation of Autologous Platelet Rich Plasma to promote the growth and regeneration of the endometrium for patients with recurrent implantation failure, poor endometrium within Assisted Reproductive Technology (ART) or Asherman's syndrome: Investigating the effect on successful pregnancy.

Not Applicable

Recruiting

• Conditions: Recurrent Implantation Failure; Asherman's Syndrome; Thin Endometrium; Reproductive Health and Childbirth - Fertility including in vitro fertilisation

• Registration Number: ACTRN12623000390684
• Lead Sponsor: Fertility North

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-04-18
• Last Update Posted: 24 April 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

i. RIF
ii. Thin endometrium, (<7mm) on either an Invitro Fertilisation (IVF) cycle or Frozen Embryo Transfer (FET) cycle
iii. A history of a cancelled IVF or FET procedure due to thin endometrium
iv. Diagnosed with Asherman's syndrome

Exclusion Criteria

i. Patients with an endometrium of >7mm and no RIF
ii. Patients with Premature Ovarian Failure (POF) due to a genetic condition e.g. Turners syndrome.
iii. Patients with Idiopathic thrombocytopenia (autoimmune platelet deficiency).
iv. Patients who are unable to undergo an IVF treatment cycle for any reason.

Study & Design

• Study Type: Interventional
• Study Design: Not specified