Comparative study of combination of Intralesional Triamcinolone and radiofrequency ablation versus Intralesional Triamcinolone in the treatment of keloids
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 176
- 试验地点
- 1
- 主要终点
- Decrease in mean POSAS score
研究概览
简要总结
This is a comparative study of combination of intralesional triamcinolone and radiofrequency ablation versus intralesional triamcinolone injection alone in treatment of keloids. Intralesional triamcinolone injection alone leads to atrophy and hypopigmentaion of surrounding skin and also there are high chance of relapse. These side effects and chances of recurrences are reduced if triamcinolone injection is combined with radiofrequency ablation. So this study is done to compare the both the modalities and give the best of the treatment to the patients. In half of the patients only intralesional triamcinolone injection 40mg/ml will be given at 3 weeks interval for 15 weeks intralesionally and in half of the patients intralesional radiofrequency ablation will be done intralesionally at 3 weeks interval for 15 weeks along with inlesional triamcinolone injection at a dose of 40mg/ml.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient in the age group 18 to 60 years and Patient giving consent for therapy are included in study.
排除标准
- •Patients of age less than 18 years or more than 60 years, pregnant and lactating women, Patient with local/systemic infection, any serious illness, extensive keloids, artificial pacemakers, metals implants and Patients who are previously treated and not giving consent are not included in study.
结局指标
主要结局
Decrease in mean POSAS score
时间窗: 15 weeks
次要结局
- to compare side effects(15 weeks)
研究者
Bhavana Chaudhary
JN MEDICAL COLLEGE, AMU