Effect of Myoma Removal on Blood Pressure and Erythropoetin Level

Not Applicable

Completed

• Conditions: Myoma; Hypertension
• Interventions: Procedure: myoma removal

• Registration Number: NCT00898170
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.

Detailed Description

Background:

Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis.

Patients \& Methods:

In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.

Study Timeline

• Study Start: 2008-05
• Primary Completion: 2009-03
• Study Completion: 2009-03
• Status Verified: 2009-05
• Study First Submitted: 2009-05-11
• Study First Submitted QC: 2009-05-11
• Last Update Submitted: 2009-05-11
• Study First Posted: 2009-05-12
• Last Update Posted: 2009-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• candidate for myoma removal by hysterectomy
• operable
• hysterectomy is indicated

Exclusion Criteria

• patient refusal
• inoperable patients
• other secondary cases of hypertension

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
myoma, with or without hypertension	myoma removal	those with myoma with or without hypertension in holter monitoring

Primary Outcome Measures

Name	Time	Method
24 hour holter monitoring of blood pressure	6 weeks

Secondary Outcome Measures

Name	Time	Method
erythropoetin level	6 weeks

Trial Locations

Locations (1)

Cardiology Ward Shiraz University of Medical Sciences; 🇮🇷 Shiraz, Fars, Iran, Islamic Republic of