The Serum Lipid Profiles in ITP: a Retrospective Study
- Conditions
- Immune Thrombocytopenia
- Registration Number
- NCT05095896
- Lead Sponsor
- Ming Hou
- Brief Summary
The project was retrospectively undertaking by Qilu Hospital of Shandong University in China. In order to investigate the correlations between platelet indices, serum lipids and bleeding symptoms in ITP.
- Detailed Description
Background: Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by increased platelet destruction and impaired thrombopoiesis. Platelet indices changes depending on the morphology and volume of platelets. Serum lipids have been found to affect platelet formation and activity in certain diseases, thus induce the corresponding variation of platelet indices.
Objectives: To investigate the correlations between platelet indices, serum lipids and bleeding symptoms in ITP.
Methods: The clinical data from 457 ITP patients were retrospectively collected and analyzed, including platelet indices, serum lipids, hemorrhage and therapeutic regimen.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 457
- Meet the diagnostic criteria for immune thrombocytopenia.
- (1) receiving platelet transfusion within 7 days or ITP-related medication within 3 months (2) treated with lipid-lowing agents, including statins, fibrates, niacin, bile sequestrant resins, ezetimibe and so on.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Platelet count at 1 month after initial therapy 1 month Platelet count was tested at 1 month after initial therapy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Qilu hospital of Shandong university
🇨🇳Jinan, Shandong, China