Evaluation efficacy and side effects of IV ibuprofen and IV acetaminophen in pain control after laparoscopic cholecystectomy.
Phase 3
- Conditions
- Cholecystit.Cholecystit
- Registration Number
- IRCT20161024030479N2
- Lead Sponsor
- Ardabil University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Patients candidate for laparoscopic cholecystectomy
Age 20 - 60 years old
Exclusion Criteria
1-Pregnancy
Have a history of asthma and other respiratory disease
Have a history of heart failure
Have a history of CRF or dialysis
Have a history of GI bleeding
HTN
Have a history of Anemia
Patients are taking warfarin
Patients are taking a combination of ACEI and furosemide
Tolerance or dependence to opioids
Allergy or hypersensitivity to ibuprofen, ASA, NSAIDs, or COX2 inhibitor
Age less than 20 years old and more than 60 years old
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of pain in the surgical site. Timepoint: 6, 12, 18 and 24 hours after surgery. Method of measurement: VAS system.
- Secondary Outcome Measures
Name Time Method ausea and vomiting. Timepoint: 6,12,18 and 24 hours after surgery. Method of measurement: N/V Score.;Shoulder pain. Timepoint: 6,12,18 and 24 hours after surgery. Method of measurement: VAS.;Sedation. Timepoint: 6,12,18 and 24 hours after surgery. Method of measurement: Ramsay score.