eolifes-Lungs: the effect of preterm birth on lung function of the children at the age of 6 months

Completed

• Conditions: respiratory problems in children born preterm; 10028971

• Registration Number: NL-OMON42563
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 135

Inclusion Criteria

The NeoLifeS cohort comprises preterm children born before 30 weeks* gestational age, and /or birth weights below 1000 grams.

Exclusion Criteria

ill (fever) at the moment of the lung function test
respiratory tract infection
oxygen or feedtubes

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints: Lung Clearance Index (LCI), airway resistance<br /><br>(R), functional residual capacity( FRC) and maximal flow at FRC (VmaxFRC) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Does high LCI at the age of 6 months predict more respiratory symptoms and<br /><br>hospitalisations due to respiratory problems in the follow up period (first<br /><br>year of life)?<br /><br>2. Is het possible to determine perinatal/ neonatal riskfactors for high LCI at<br /><br>the age of 6 months?</p><br>