Transfusion and treatment of severe anaemia in African children trial

Phase 3

Completed

• Conditions: Severe anaemia; Haematological Disorders; Nutritional anaemias

• Registration Number: ISRCTN84086586
• Lead Sponsor: Imperial College London (UK)

Brief Summary

2015 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/26715196 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31365799 results (added 01/08/2019) 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31365800 results (added 01/08/2019) 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31537373 results (added 23/09/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34325680/ Secondary analysis (added 02/08/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35147242/ (added 14/02/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-02-11
• Study Completion: 2019-12-30
• Last Update Posted: 1 March 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1565

Inclusion Criteria

Children will be recruited at the point of hospital admission
1. Aged 2 months to 12 years
2. Severe anaemia (SA) (Hb<6g/dl) within 2h of admission to hospital
3. Carer willing/able to provide consent

Exclusion Criteria

1. Malignancy
2. Surgery
3. Acute trauma
4. Signs of bi-ventricular heart failure

Study & Design

• Study Type: Interventional
• Study Design: Not specified