A study for effectiveness of local anaesthetic drugs in abdominal hysterectomy surgery
Phase 4
Completed
- Conditions
- Health Condition 1: null- Awaited for abdominal hysterectomy operation
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
1. Adult female patients, aged between 30 to 65 yrs
2. BMI 18.5 to 29.9 kg/meter2
3. ASA physical status I & II.
4. Patients scheduled for elective abdominal hysterectomy under lumbar epidural anaesthesia.
Exclusion Criteria
a) Patient refusal.
b) Any contraindication to epidural anaesthesia â??
i. Infection at the site of injection
ii. Coagulopathy
iii. Neurological disorders and psychiatric disorder
iv. Haemodynamically compromised patients
v. Sepsis
vi. Gross anatomical abnormality of vertebral column.
vii. Known allergy to either bupivacaine or ropivacaine or fentanyl.
viii. Patients on chronic antiplatelet drugs and anticoagulants.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To conclude that in the present study using 0.5% bupivacaine with fentanyl and 0.75% ropivacaine with fentanyl epidurally, ropivacaine produced an earlier onset but similar duration of sensory block. The onset, quality and duration of motor block were comparable in both the groups.Timepoint: During hysterectomy operation for two hours
- Secondary Outcome Measures
Name Time Method In hemodynamics, heart rate was comparable in both groups but blood pressures (SBP, MAP, DBP) was decrease significantly in bupivacaine group after 20min of administration of the epidural study drug.Timepoint: Post operative assessment for 24hours