Subacute Traumatic Spinal cord injury
Not Applicable
- Conditions
- Traumatic spinal cord injury.Other of spine injury trunk other specified
- Registration Number
- IRCT2012122611889N1
- Lead Sponsor
- Shefa Neuroscience Research Center, Khatamolanbia Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Inclusion Criteria : Definite paraplegic classification supported Franklin (A);
Disease progression between 2-3 weeks; SCI region (T1-T10); Age range 15-55 years
Exclusion Criteria
History of cortical brain damage;
GCS<10 (Coma);
MS;
Any major systemic or psychiatric illness;
History of hypertension;
Diabetes;
Any major pathology in brain or spinal cord;
Pregnancy;
Any major systematic or psychiatric illness before trauma;
Any coexisting neurodegenerative disease;
History of stem cell;
history of Hematologic or lymphoproliferative transplantation;
History of spinal cord injury or spinal surgery;
History of Hepatitis and HIV
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life. Timepoint: Before and 6 months after intervention. Method of measurement: Asia (american spinal injury association) Score, SCIM(spinal cord independent measure) questionnaire.;Disability. Timepoint: Before and 6 months after intervention. Method of measurement: Asia(American Spinal Injury Association) Score, SCIM(Spinal Cord Independent Measure) questionnaire.;Electrophysiologic parameters (EMG,NCV- SSEP,MMEP). Timepoint: Before and 6 months after intervention. Method of measurement: EMG, NCV, Evoked.;Urinary and fecal incontinency. Timepoint: Six months. Method of measurement: UDS(Urodynamic Study).
- Secondary Outcome Measures
Name Time Method Forced vital capacity. Timepoint: six months. Method of measurement: Spirometry (PFT).;Muscle Strength. Timepoint: six months after intervention. Method of measurement: MRC, Questionnaire.;Side effects (Transplantation site hematoma and edema spinal cord- Anaphylaxis shock ). Timepoint: After intervention and 6 months after intervention. Method of measurement: Questionnaire,Examination, MRI.