Effect and safety of 5% nicotinamide cream in the treatment of actinic keratosis
- Conditions
- Actinic KeratosisC04.834
- Registration Number
- RBR-6m7tyhf
- Lead Sponsor
- Faculdade de Medicina Julio de Mesquita Filho
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Sign the Free and Informed Consent Form; age over 18 years of both sexes; present at least three and at most ten lesions clinically compatible with actinic keratoses on each forearm, bilaterally.
Actinic keratoses fewer than three or more than ten on each forearm; selected treatment area that has atypical clinical appearance or other extensive dermatoses on the forearms; presence of skin tumors in the treatment area; current and previous clinical diagnosis or evidence of any medical condition that exposes the patient to increased risks, interferes with the safety or efficacy of the proposed treatment; present hypersensitivity or allergy to any of the substances being studied; patients using any systemic or topical immunosuppressant substance and oral retinoid; immunocompromised individuals; coagulation disorders; suspected or confirmed pregnancy; women of childbearing age not using contraceptive methods; breastfeeding women; previous treatments for actinic keratoses in the last six months.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method An absence of new actinic keratoses on the forearms is expected after the application of 5% nicotinamide cream within a period of 70 days, which will be verified by counting the actinic keratoses, based on the verification of a variation of at least 15% in the pre and post measurements -intervention.<br>
- Secondary Outcome Measures
Name Time Method