The benefit of Nicotinamide + Vitamin C + Hyaluronic Acid, compared to Hydroquinone in the treatment of Melasma

Not Applicable

Recruiting

• Conditions: Melasma; L989

• Registration Number: RBR-4mkfmr8
• Lead Sponsor: Faculdade de Medicina de Botucatu, Universidade Estadual Paulista

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-03-20
• Last Update Posted: 29 May 2023
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women; age between 18 and 60 years; with facial melasma; Fitzpatrick phototypes 2 to 5

Exclusion Criteria

Pregnant or lactating women; women using other bleaches; women who refuse to be photographed

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in the severity of melasma that will be evaluated through the mMASI Score (modified Melasma Area and Severity Index) and a percentage reduction of at least 10% is expected at the end of treatment when compared to the beginning

Secondary Outcome Measures

Name	Time	Method
Global clinical improvement is expected, assessed using the MELASQoL and GAIS scale